Thromboxane synthase Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Thromboxane synthase Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A5173
• Supplier Catalog Number: A5173
• Alternative Catalog Number: ABB-A5173-20UL,ABB-A5173-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14, Thromboxane synthase

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 61kDa
• NCBI: 6916
• UniProt: P24557
• Purity: Affinity purification
• Target: TBXAS1

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Cancer,Signal Transduction,Cell Biology Developmental Biology,Endocrine Metabolism,Cardiovascular,Heart,Cardiovascular diseases,Heart disease. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Thromboxane synthase Rabbit mAb (A5173) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 90s.