PIAS2 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: PIAS2 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A5203
• Supplier Catalog Number: A5203
• Alternative Catalog Number: ABB-A5203-20UL,ABB-A5203-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: DIP, MIZ1, SIZ2, ARIP3, PIASX, ZMIZ4, PIAS2

Product Description

This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 45kDa/63kDa/68kDa
• NCBI: 9063
• UniProt: O75928
• Purity: Affinity purification
• Target: PIAS2

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Cell Biology Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology Inflammation,Jak-Stat-IL-6 Receptor Signaling Pathway. Shipping: Ice Bag

Images

Western blot analysis of various lysates using PIAS2 Rabbit mAb (A5203) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.