P2RY2 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: P2RY2 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A5779
• Supplier Catalog Number: A5779
• Alternative Catalog Number: ABB-A5779-20UL,ABB-A5779-100UL,ABB-A5779-1000UL,ABB-A5779-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: P2U, HP2U, P2U1, P2UR, P2Y2, P2RU1, P2Y2R, P2RY2

Product Description

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 42kDa
• NCBI: 5029
• UniProt: P41231
• Purity: Affinity purification
• Sequence: CHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
• Target: P2RY2
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Neuroscience. Shipping: Ice Bag

Images

Western blot analysis of lysates from Mouse skeletal muscle, using P2RY2 Rabbit pAb (A5779) at 1:400 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 30s.