Islet1 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: Islet1 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A6383
• Supplier Catalog Number: A6383
• Alternative Catalog Number: ABB-A6383-20UL,ABB-A6383-100UL,ABB-A6383-500UL,ABB-A6383-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: Isl-1, ISLET1, Islet1

Product Description

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 39kDa
• NCBI: 3670
• UniProt: P61371
• Purity: Affinity purification
• Sequence: MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKT
• Target: ISL1
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cell Biology Developmental Biology,Endocrine Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience, Cell Type Marker,Stem Cells,Neural Stem Cells,Cardiovascular,Heart,Cardiogenesis,Neuron marker. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Islet1 Rabbit pAb (A6383) at 1:500 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 5s.