SRSF4 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: SRSF4 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A6978
• Supplier Catalog Number: A6978
• Alternative Catalog Number: ABB-A6978-100UL,ABB-A6978-20UL,ABB-A6978-1000UL,ABB-A6978-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: SFRS4, SRP75, SRSF4

Product Description

Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome, acute myeloid leukemia, clear cell renal cell carcinoma, and colon adenocarcinoma.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 57kDa
• NCBI: 6429
• UniProt: Q08170
• Purity: Affinity purification
• Sequence: MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
• Target: SRSF4
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling. Shipping: Ice Bag

Images

Western blot analysis of various lysates, using SRSF4 Rabbit pAb (A6978) at 1:2000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.