ADM Rabbit pAb, Unconjugated

Product Overview

• Article Name: ADM Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-A8659
• Supplier Catalog Number: A8659
• Alternative Catalog Number: ABB-A8659-20UL, ABB-A8659-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: AM, PAMP, ADM

Product Description

The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration.

Product Properties

• Molecular Weight: 20kDa
• NCBI: 133
• UniProt: P35318
• Purity: Affinity purification
• Target: ADM

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse, ResearchArea: Cancer,Signal Transduction,Cell Biology Developmental Biology,Growth factors,Endocrine Metabolism,Neuroscience,Cardiovascular,Angiogenesis,Hypoxia.

Images

Western blot analysis of lysates from Mouse kidney, using ADM Rabbit pAb (A8659) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 15s.