SFRP1 Rabbit mAb, Unconjugated

Product Overview

• Article Name: SFRP1 Rabbit mAb, Unconjugated
• Biozol Catalog Number: ABB-A9656
• Supplier Catalog Number: A9656
• Alternative Catalog Number: ABB-A9656-20UL, ABB-A9656-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: FRP, FRP1, FrzA, FRP-1, SARP2, SFRP1

Product Description

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

Product Properties

• Molecular Weight: 35kDa
• NCBI: 6422
• UniProt: Q8N474
• Purity: Affinity purification
• Target: SFRP1

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Cell biology developmental biology,Apoptosis,Ubiquitin,Wnt beta-Catenin signaling pathway,Neuroscience,Stem cells.

Images

Western blot analysis of various lysates using SFRP1 Rabbit mAb (A9656) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.