Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation:
Unconjugated
Alternative Names:
MTND1, ND1, MT-ND1
Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrial membrane. Part of mitochondrial respiratory chain complex I. Implicated in several diseases, including MELAS syndrome, neurodegenerative disease (multiple), optic nerve disease (multiple), toxic shock syndrome, and type 2 diabetes mellitus. Biomarker of Alzheimers disease, Parkinsons disease, and multiple sclerosis.
Western blot analysis of various lysates using MT-ND1 Rabbit mAb (A9743) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s.
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