Phospho-IRS1-S312 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-IRS1-S312 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0181
• Supplier Catalog Number: AP0181
• Alternative Catalog Number: ABB-AP0181-20UL, ABB-AP0181-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: HIRS-1, Phospho-IRS1-S312

Product Description

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

Product Properties

• Concentration: WB
• Molecular Weight: 132kDa
• NCBI: 3667
• UniProt: P35568
• Purity: Affinity purification
• Target: IRS1

Application Notes

• Application Dilute: WB,1:500 - 1:2000
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Protein phosphorylation,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology Developmental Biology,Growth factors,Endocrine Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology Inflammation,Neuroscience, Cell Type Marker,Cardiovascular,Heart,Cardiovascular diseases,Heart disease.

Images

Western blot analysis of lysates from 293 cells, using Phospho-IRS1-S312 Rabbit pAb (AP0181).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.