Phospho-YWHAZ-S58 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-YWHAZ-S58 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0195
• Supplier Catalog Number: AP0195
• Alternative Catalog Number: ABB-AP0195-20UL, ABB-AP0195-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: HEL4, YWHAD, KCIP-1, HEL-S-3, POPCHAS, HEL-S-93, 14-3-3-zeta, Phospho-YWHAZ-S58

Product Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5 UTR but that encode the same protein have been identified for this gene.

Product Properties

• Molecular Weight: 28kDa
• NCBI: 7534
• UniProt: P63104
• Purity: Affinity purification
• Target: YWHAZ

Application Notes

• Application Dilute: WB,1:500 - 1:2000|IF/ICC,1:100 - 1:200
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,RNA Binding,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cell Cycle,Cell Cycle Control-G2 M DNA Damage Checkpoint,Cytoskeleton,Actins,Immunology Inflammation,Neuroscience, Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neurodegenerative Diseases Markers.

Images

Western blot analysis of lysates from HeLa cells, using Phospho-YWHAZ-S58 Rabbit pAb (AP0195).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.