Phospho-Ezrin-T567 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-Ezrin-T567 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0207
• Supplier Catalog Number: AP0207
• Alternative Catalog Number: ABB-AP0207-100UL, ABB-AP0207-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: CVL, CVIL, VIL2, HEL-S-105, Phospho-Ezrin-T567

Product Description

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Product Properties

• Concentration: WB
• Molecular Weight: 69kDa
• NCBI: 7430
• UniProt: P15311
• Purity: Affinity purification
• Target: EZR

Application Notes

• Application Dilute: WB,1:500 - 1:2000
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,RNA Binding,Protein phosphorylation,Cancer,Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Immunology Inflammation,B Cell Receptor Signaling Pathway.

Images

Western blot analysis of lysates from MDA cells, using Phospho-Ezrin-T567 Rabbit pAb (AP0207).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.