Phospho-IkappaBalpha-Y42 Rabbit pAb, Unconjugated
Catalog Number:
ABB-AP0420
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| Article Name: | Phospho-IkappaBalpha-Y42 Rabbit pAb, Unconjugated |
| Biozol Catalog Number: | ABB-AP0420 |
| Supplier Catalog Number: | AP0420 |
| Alternative Catalog Number: | ABB-AP0420-20UL, ABB-AP0420-100UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | IKBA, MAD-3, NFKBI, EDAID2, Phospho-IkappaBalpha-Y42 |
| This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
| Application Dilute: | WB,1:500 - 1:2000 |
| Application Notes: | Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Protein phosphorylation,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,ATM Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling. |
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Western blot analysis of lysates from HeLa cellss, using Phospho-IkappaBalpha-Y42 Rabbit pAb (AP0420). Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. |
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