Phospho-Tyk2-Y1054/1055 Rabbit pAb, Unconjugated
Catalog Number:
ABB-AP0543
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| Article Name: | Phospho-Tyk2-Y1054/1055 Rabbit pAb, Unconjugated |
| Biozol Catalog Number: | ABB-AP0543 |
| Supplier Catalog Number: | AP0543 |
| Alternative Catalog Number: | ABB-AP0543-100UL,ABB-AP0543-1000UL,ABB-AP0543-500UL,ABB-AP0543-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | JTK1, IMD35, Phospho-Tyk2-Y1054/1055 |
| This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat, ResearchArea: Protein phosphorylation,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Immunology Inflammation. |
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Western blot analysis of lysates from NIH/3T3 cells, using Phospho-Tyk2-Y1054/1055 Rabbit pAb (AP0543) at 1:1000 dilution. NIH/3T3 cells were treated with IFN-alpha (100 ng/ml) at 37°C for 30 minutes after serum-starvation overnight. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. Detection: ECL Enhanced Kit (RM00021). Exposure time: 180s. |
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