Phospho-STK11-T189 Rabbit pAb, Unconjugated
Catalog Number:
ABB-AP0603
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| Article Name: | Phospho-STK11-T189 Rabbit pAb, Unconjugated |
| Biozol Catalog Number: | ABB-AP0603 |
| Supplier Catalog Number: | AP0603 |
| Alternative Catalog Number: | ABB-AP0603-100UL,ABB-AP0603-1000UL,ABB-AP0603-500UL,ABB-AP0603-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | PJS, LKB1, hLKB1, Phospho-STK11-T189 |
| The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Protein phosphorylation,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect. |
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Western blot analysis of lysates from A-431 cells, using Phospho-STK11-T189 Rabbit pAb (A2122). A-431 cells were treated with 10% FBS for after serum-starvation overnight. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (RM00020). |
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