Phospho-NMDAR1-S890 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-NMDAR1-S890 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0826
• Supplier Catalog Number: AP0826
• Alternative Catalog Number: ABB-AP0826-100UL, ABB-AP0826-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: NR1, MRD8, GluN1, NMDA1, DEE101, NDHMSD, NDHMSR, NMD-R1, NMDAR1, Phospho-NMDAR1-S890

Product Description

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Product Properties

• Molecular Weight: 105kDa
• NCBI: 2902
• UniProt: Q05586
• Purity: Affinity purification
• Target: GRIN1

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Rat, ResearchArea: Protein phosphorylation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Dopamine Signaling in Parkinsons Disease.

Images

Western blot analysis of lysates from C6 cells, using Phospho-NMDAR1-S890 Rabbit pAb (AP0826) at 1:1000 dilution. C6 cells were treated with PMA/TPA (200nM) for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.