Phospho-Axl-Y702 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-Axl-Y702 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0848
• Supplier Catalog Number: AP0848
• Alternative Catalog Number: ABB-AP0848-100UL,ABB-AP0848-20UL,ABB-AP0848-500UL,ABB-AP0848-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: ARK, UFO, JTK11, Tyro7, Phospho-Axl-Y702

Product Description

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 98kDa
• NCBI: 558
• UniProt: P30530
• Purity: Affinity purification
• Sequence: GDYYR
• Target: AXL
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:100 - 1:500|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology Developmental Biology,Cell Cycle,Immunology Inflammation.

Images

Western blot analysis of lysates from A-549 cells, using Phospho-Axl-Y702 Rabbit pAb (AP0848) at 1:400 dilution. A-549 cells were treated with Gas6 (400 ng/ml) at 37°C for 5 minutes.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.