Phospho-STK3/MST2-T117 Rabbit pAb

Product Overview

• Article Name: Phospho-STK3/MST2-T117 Rabbit pAb
• Biozol Catalog Number: ABB-AP0934
• Supplier Catalog Number: AP0934
• Alternative Catalog Number: ABB-AP0934-100UL,ABB-AP0934-20UL,ABB-AP0934-500UL,ABB-AP0934-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Alternative Names: KRS1, MST2, Phospho-STK3/MST2-T117

Product Description

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 56kDa
• NCBI: 6788
• UniProt: Q13188
• Purity: Affinity purification
• Sequence: NKTLI
• Target: STK3
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:100 - 1:500|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Kinase,Serine threonine kinases,Cell Biology Developmental Biology,Apoptosis,Autophagy.

Images

Western blot analysis of lysates from NIH/3T3 cells, using Phospho-STK3/MST2-T117 Rabbit pAb (AP0934) at 1:400 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.