Phospho-STK3/MST2-T384 Rabbit pAb
Catalog Number:
ABB-AP0935
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| Article Name: | Phospho-STK3/MST2-T384 Rabbit pAb |
| Biozol Catalog Number: | ABB-AP0935 |
| Supplier Catalog Number: | AP0935 |
| Alternative Catalog Number: | ABB-AP0935-100UL,ABB-AP0935-20UL,ABB-AP0935-1000UL,ABB-AP0935-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Alternative Names: | KRS1, MST2, Phospho-STK3/MST2-T384 |
| This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Kinase,Serine threonine kinases,Cell Biology Developmental Biology,Apoptosis,Autophagy. |
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Western blot analysis of various lysates using Phospho-STK3/MST2-T384 Rabbit pAb (AP0935) at 1:1000 dilution. HeLa cells were treated with Calyculin A (100 nM) at 37°C for 30 minutes. NIH/3T3 cells were treated with Calyculin A (100 nM) at 37°C for 30 minutes. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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