Phospho-MCL1-T163 Rabbit pAb

Product Overview

• Article Name: Phospho-MCL1-T163 Rabbit pAb
• Biozol Catalog Number: ABB-AP0943
• Supplier Catalog Number: AP0943
• Alternative Catalog Number: ABB-AP0943-100UL, ABB-AP0943-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Alternative Names: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Phospho-MCL1-T163

Product Description

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Product Properties

• Molecular Weight: 37kDa
• NCBI: 4170
• UniProt: Q07820
• Purity: Affinity purification
• Target: MCL1

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse, ResearchArea: Protein phosphorylation,Cancer,Invasion and Metastasis,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Endocrine Metabolism,Immunology Inflammation,Jak-Stat-IL-6 Receptor Signaling Pathway.

Images

Western blot analysis of lysates from NIH/3T3 cells, using Phospho-MCL1-T163 Rabbit pAb (AP0943) at 1:1000 dilution. NIH/3T3 cells were treated with PMA (80 nM) for overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.