Phospho-RELB-S573 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-RELB-S573 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP1297
• Supplier Catalog Number: AP1297
• Alternative Catalog Number: ABB-AP1297-20UL,ABB-AP1297-100UL,ABB-AP1297-500UL,ABB-AP1297-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: IREL, I-REL, IMD53, REL-B, Phospho-RELB-S573

Product Description

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin, nucleus, and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 62kDa
• NCBI: 5971
• UniProt: Q01201
• Purity: Affinity purification
• Sequence: LLSPG
• Target: RELB
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway.

Images

Western blot analysis of lysates from A20, using Phospho-RELB-S573 Rabbit pAb (AP1297) at 1:500 dilution. A20 cells were treated with PMA/TPA (200 nM) at 37°C for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.