Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
PE/Cy7
Alternative Names:
Igm, muH, Igh6, Igh-6, Igh-M
Enables several functions, including antigen binding activity, identical protein binding activity, and immunoglobulin receptor binding activity. Acts upstream of or within several processes, including early endosome to late endosome transport, immunoglobulin mediated immune response, and positive regulation of B cell proliferation. Located in external side of plasma membrane, extracellular space, and perinuclear region of cytoplasm. Part of B cell receptor complex and immunoglobulin complex, circulating. Is expressed in several structures, including brain, hemolymphoid system, and liver. Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human IGHM (immunoglobulin heavy constant mu).
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with PE/Cyanine7 Rabbit IgG isotype control (5 µl/Test,left) or PE/Cyanine7 Rabbit anti-Mouse IgM mAb (AS175,5 µl/Test,right).
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