Serum, Plasma, Cell Culture Supernatant, and other biological fluids
Conjugation:
Biotin
Alternative Names:
IL2, IL-2, TCGF, lymphokine
Enables cytokine activity and interleukin-2 receptor binding activity. Involved in negative regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of macromolecule metabolic process, and regulation of lymphocyte activation. Located in extracellular space. Is expressed in liver, omental bursa, thymus, and thymus primordium. Used to study Sjogrens syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including Takayasus arteritis, auditory system disease (multiple), autoimmune disease (multiple), carcinoma (multiple), and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2).
