Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus, positive regulation of cell communication, and positive regulation of metabolic process. Located in extracellular space. Used to study several diseases, including acute necrotizing pancreatitis, disseminated intravascular coagulation, hypertension (multiple), impotence, and steatotic liver disease. Biomarker of several diseases, including acute necrotizing pancreatitis, artery disease (multiple), auditory system disease (multiple), gastrointestinal system cancer (multiple), and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), eye disease (multiple), gastrointestinal system cancer (multiple), glucose metabolism disease (multiple), and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6).
