Serum, plasma, cell culture supernatant, and other biological fluids.
Conjugation:
Biotin
Alternative Names:
Il-4, BSF-1, IL4
Enables cytokine activity. Involved in several processes, including innate immune response in mucosa, positive regulation of metabolic process, and regulation of gene expression. Acts upstream of or within several processes, including T-helper cell differentiation, positive regulation of macromolecule metabolic process, and regulation of lymphocyte activation. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain, gut, hemolymphoid system gland, liver, and placenta. Used to study Sjogrens syndrome, atopic dermatitis, and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple), autoimmune disease (multiple), hepatitis B, hepatitis C, and pancreatic cancer (multiple). Orthologous to human IL4 (interleukin 4).
