Serum, Plasma, Cell Culture Supernatant, and other biological fluids
Conjugation:
HRP
Alternative Names:
Tnfa, RATTNF, TNF-alpha, TNFalpha
Enables tumor necrosis factor receptor binding activity. Involved in several processes, including positive regulation of cell communication, positive regulation of macromolecule metabolic process, and positive regulation of neuron death. Located in several cellular components, including external side of plasma membrane, extracellular space, and neuronal cell body. Used to study several diseases, including cerebrovascular disease (multiple), liver disease (multiple), peptic esophagitis, perinatal necrotizing enterocolitis, and periventricular leukomalacia. Biomarker of several diseases, including brain disease (multiple), congestive heart failure (multiple), inflammatory bowel disease (multiple), lung disease (multiple), and non-alcoholic fatty liver disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple), autoimmune disease (multiple), eye disease (multiple), lung disease (multiple), and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).