The protein is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.
Lyophilized from a 0.22 µm filtered solution of 50mM HEPES, 100mM NaCl, pH 7.5.Contact us for customized product form or formulation.
Target:
ISG15
Application Dilute:
Lyophilized from a 0.22 µm filtered solution of 50mM HEPES, 100mM NaCl, pH 7.5.Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human ISG15 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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