Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heatshock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it isthought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to thisprotein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer andnucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm prematurerupture of membranes.
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Target:
Serpin H1/HSP47
Application Dilute:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human Serpin H1/HSP47 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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