NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killercell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteinspreferentially expressed in NK cells. Members of this proteins is characterized by the type II membraneorientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells orB-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B,NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing aC-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NKcells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in thenomenclature of CD antigens.
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Target:
NKG2-2A/KLRC1/CD159a
Application Dilute:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Bio-Markers & CD Antigens,Biosimilar Drug Targets
Recombinant Human NKG2-2A/KLRC1/CD159a Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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