Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is takenup in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits ofthe light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsulecells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and releasein different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost allliving organisms can produce this protein, including algae, bacteria, higher plants, and animals.
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Contact us for customized product form or formulation.
Target:
Ferritin heavy chain/FTH1
Application Dilute:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Cytokines & Cytokine Receptors
Recombinant Human Ferritin heavy chain/FTH1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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