This protein is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohns disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Lyophilized from a 0.22 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Target:
IL-1R7/IL-18RAcP/CD218b
Application Dilute:
Lyophilized from a 0.22 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Bio-Markers & CD Antigens,Interleukin
Recombinant Human&,nbsp, IL-18 R beta/IL-1 R7/CD218b&,nbsp, Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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