ASFV structural protein p30 is a significant immunogen reported to induce neutralizing antibodies against it. The p30 interacts with heterologous nuclear ribonucleoprotein K (hnRNPK) in the host cell and could downregulate the host cell mRNA translation (Hernaez et al., 2008). Moreover, p30 is an excellent diagnostic marker for ASFV, and anti-p30 antibodies can be detected as early as eight days post-infection (Gomez-Puertas et al., 1998).We and others previously showed the epitopic domains of the p30 protein, which could potentially generate the host immune response (Afonso et al., 1992, Imdhiyas et al., 2022, Petrovan et al., 2019).
