Biotinylated Recombinant Human MHC class I polypeptide-related sequence B/MIC-B Protein

Catalog Number: ABB-RP02442B
Article Name: Biotinylated Recombinant Human MHC class I polypeptide-related sequence B/MIC-B Protein
Biozol Catalog Number: ABB-RP02442B
Supplier Catalog Number: RP02442B
Alternative Catalog Number: ABB-RP02442B-100UG,ABB-RP02442B-500UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Immunogen: Ala23-Gly298
Alternative Names: MICB,PERB11.2
MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 34.4 kDa
NCBI: 4277
UniProt: Q29980
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Form: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Target: MIC-B
Application Dilute: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein