Biotinylated Recombinant Human B7-H2/ICOSLG/CD275 Protein

Catalog Number: ABB-RP02576B
Article Name: Biotinylated Recombinant Human B7-H2/ICOSLG/CD275 Protein
Biozol Catalog Number: ABB-RP02576B
Supplier Catalog Number: RP02576B
Alternative Catalog Number: ABB-RP02576B-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Immunogen: Asp19-Ser258
Alternative Names: CD275, B7H2, B7-H2, B7RP-1, GL50, ICOSL, ICOS-L, ICOSLG, B7RP1, LICOS, ICOS ligand, B7-H2B7-related protein 1, B7RP-1, B7RP1B7-like protein Gl50
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 29.5 kDa
NCBI: 23308
UniProt: O75144
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Form: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Target: B7-H2/ICOSLG/CD275
Application Dilute: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Bio-Markers & CD Antigens