Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein

Catalog Number: ABB-RP02598B
Article Name: Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein
Biozol Catalog Number: ABB-RP02598B
Supplier Catalog Number: RP02598B
Alternative Catalog Number: ABB-RP02598B-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Immunogen: Leu34-Glu125
Alternative Names: AAT5, ACVRLK4, ALK-5, LDS1A, LDS2A, SKR4, tbetaR-I, TGFB1R1, TGF-beta RI, TGFbetaRI, TGFBR1, TGF-bRI, TGFR-1, tbetaR-I, TGF-beta RI, TGFbetaRI
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR?98?5p. miR?98?5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 38.2 kDa
NCBI: 7046
UniProt: P36897
Purity: 95 % as determined by Tris-Bis PAGE.
Form: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Target: TGFR-1/ALK-5
Application Dilute: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein