Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein, Human

Catalog Number: ABB-RP02639
Article Name: Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein, Human
Biozol Catalog Number: ABB-RP02639
Supplier Catalog Number: RP02639
Alternative Catalog Number: ABB-RP02639-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Monkey
Immunogen: Ile21-Met119
Alternative Names: Beta-2-microglobulin,B2M
The genetic and functional analysis of beta2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 12.7 kDa
NCBI: 712428
UniProt: Q8SPW0
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target: Cynomolgus B2M/beta 2-Microglobulin
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein