Recombinant Cynomolgus LILRB4/ILT-3/CD85k Protein, Human

Product Overview

• Article Name: Recombinant Cynomolgus LILRB4/ILT-3/CD85k Protein, Human
• Biozol Catalog Number: ABB-RP02649
• Supplier Catalog Number: RP02649
• Alternative Catalog Number: ABB-RP02649-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Immunogen: Gln22-Glu259
• Alternative Names: HM18, ILT3, ILT-3, LILRB4, LIR5, CD85K

Product Description

LILRB4,also known as CD85k and LIR-5, ILT3,? is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 27.2 kDa
• NCBI: 107128256
• UniProt: XP_015297198.1
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target: Cynomolgus LILRB4/CD85k/ILT3

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein