Recombinant Human IL-15RA&IL-15 Protein

Catalog Number: ABB-RP02654
Article Name: Recombinant Human IL-15RA&IL-15 Protein
Biozol Catalog Number: ABB-RP02654
Supplier Catalog Number: RP02654
Alternative Catalog Number: ABB-RP02654-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Immunogen: Ile31-Ser108(IL-15RA)&Asn49-Ser162(IL-15)
Alternative Names: IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha1,Interleukin-15,IL-15,IL15
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 23.8 kDa
NCBI: 3601
UniProt: Q13261
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target: IL-15RA&amp;IL-15
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human IL-15RA&,amp,IL-15 Protein was determined by Tris-Bis PAGE under reducing conditions.
The purity of Human IL-15RA&,IL-15 is greater than 95% as determined by SEC-HPLC.
Immobilized Human IL-15RA&,IL-15, His Tag at 1µg/ml (100µl/well) on the plate. Dose response curve for Human IL-2 R beta&,IL-2 R gamma, hFc Tag with the EC<,sub>,50<,/sub>, of 0.11µg/ml determined by ELISA.
Human IL-2 R beta&,IL-2 R gamma, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-15Ra&,IL-15, His Tag with an affinity constant of 0.084 nM as determined in SPR assay (Biacore T200).