Recombinant Human AFP (HLA-A*02:01) Complex Protein

Product Overview

• Article Name: Recombinant Human AFP (HLA-A*02:01) Complex Protein
• Biozol Catalog Number: ABB-RP02693
• Supplier Catalog Number: RP02693
• Alternative Catalog Number: ABB-RP02693-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Immunogen: Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and PLFQVPEPV peptide
• Alternative Names: Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-feto, AFP, HPAFP, AFPD, FETA, MHC

Product Description

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 50.4 kDa
• UniProt: A0A140T913
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target: AFP (HLA-A*02:01) Complex

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein