Recombinant Human Survivin (HLA-A*02:01) Complex Tetramer Protein

Product Overview

• Article Name: Recombinant Human Survivin (HLA-A*02:01) Complex Tetramer Protein
• Biozol Catalog Number: ABB-RP02697
• Supplier Catalog Number: RP02697
• Alternative Catalog Number: ABB-RP02697-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Immunogen: Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and LMLGEFLKL peptide
• Alternative Names: Survivin, MHC, MHC I, BIRC5, API4, EPR-1, IAP4, survivin variant 3 alpha

Product Description

Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers, consequently, it has received significant attention as a potential oncotherapeutic target.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 258 kDa
• UniProt: A0A140T913
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target: Survivin (HLA-A*02:01) Complex Tetramer

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein