Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein

Product Overview

• Article Name: Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein
• Biozol Catalog Number: ABB-RP02712
• Supplier Catalog Number: RP02712
• Alternative Catalog Number: ABB-RP02712-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Immunogen: Phe31-Val992(ITGAV)&Gly22-Asn707(ITGB6)
• Alternative Names: Integrin alpha V beta 6, ITGAV&ITGB6

Product Description

ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion . ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 .

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 114 kDa (ITGAV)&amp;79.1 kDa (ITGB6)
• NCBI: 3685
• UniProt: P06756
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target: Integrin alpha V beta 6 (ITGAV&amp;ITGB6) Heterodimer

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein