Recombinant Cynomolgus IL-23A&Mouse IL-12B Protein, Human

Product Overview

• Article Name: Recombinant Cynomolgus IL-23A&Mouse IL-12B Protein, Human
• Biozol Catalog Number: ABB-RP02725
• Supplier Catalog Number: RP02725
• Alternative Catalog Number: ABB-RP02725-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey, Mouse
• Immunogen: Val22-Pro189(Cynomolgus IL-23 alpha)&Met23-Ser335(Mouse IL-12 beta)
• Alternative Names: IL23 alpha, IL12 beta, IL23 alpha&IL12 beta

Product Description

Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common beta subunit p40 and the specific cytokine alpha subunit p35 and p19, respectively. IL-12 signals via the IL-12Rbeta1IL-12Rbeta2 receptor complex, and IL-23 uses also IL-12Rbeta1 but engages IL-23R as second receptor.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 19.5 kDa(Cynomolgus IL-23 alpha), 35.8 kDa(Mouse IL-12 beta)
• NCBI: 16160
• UniProt: A0A2K5TLV4
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target: Cynomolgus IL-23 alpha&amp; IL-12 beta

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein