Recombinant Mouse MME/Neprilysin/CD10 Protein, Human

Catalog Number: ABB-RP02735
Article Name: Recombinant Mouse MME/Neprilysin/CD10 Protein, Human
Biozol Catalog Number: ABB-RP02735
Supplier Catalog Number: RP02735
Alternative Catalog Number: ABB-RP02735-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Mouse
Immunogen: Tyr52-Trp750
Alternative Names: Neprilysin, Atriopeptidase, Enkephalinase, NEP, Neutral, SFE, CD10, MME, CALLA, DKFZp686O16152, MGC126681, MGC126707
CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 81.1 kDa
NCBI: 17380
UniProt: Q61391
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target: CD10/MME
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein