Recombinant Human Thrombopoietin R/MPL/CD110 Protein
Biozol Catalog Number:
ABB-RP02785
Supplier Catalog Number:
RP02785
Alternative Catalog Number:
ABB-RP02785-100UG
Manufacturer:
ABclonal
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Immunogen:
Gln26-Trp491
Alternative Names:
TPO-R, CD110, MPL, c-Mpl, MPLV, K12
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Cytokines & Cytokine receptors,Cell Culture related
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