Cxcl13, Blc, Scyb13,C-X-C motif chemokine 13, B lymphocyte chemoattractant
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
Lyophilized from 0.22 µm filtered solution in 50mM Tris, 500mM NaCl (pH 7.5). Normally 8% mannitol is added as protectant before lyophilization.
Target:
Cxcl13, Blc, Scyb13
Application Dilute:
Lyophilized from 0.22 µm filtered solution in 50mM Tris, 500mM NaCl (pH 7.5). Normally 8% mannitol is added as protectant before lyophilization.
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water., ResearchArea: Cytokines & Cytokine receptors
Recombinant Mouse CXCL13/BLC Protein was determined by Bis-Tris PAGE under reducing conditions with Coomassie Blue.
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