Recombinant Human TSHR Protein, Virus

Catalog Number: ABB-RP03264
Article Name: Recombinant Human TSHR Protein, Virus
Biozol Catalog Number: ABB-RP03264
Supplier Catalog Number: RP03264
Alternative Catalog Number: ABB-RP03264-50UG
Manufacturer: ABclonal
Host: Virus
Category: Proteine/Peptide
Species Reactivity: Human
Immunogen: Gly21-Gly413
Alternative Names: Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSHR, TSH-R, LGR3, CHNG1, TSHR-I
Thyroid-stimulating hormone receptor (TSHR) is the receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. TSH is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. The activity of TSHR is mediated by G proteins which activate adenylate cyclase.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 46.1 kDa
NCBI: 7253
UniProt: P16473
Purity: 85 % as determined by SDS-PAGE.
Form: Lyophilized from a 0.22 µm filtered solution of 50 mM Tris, 150 mM NaCl, 10% Glycerol, 1 mM TCEP, pH 7.5. Contact us for customized product form or formulation.
Sequence: GMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRA
Target: TSHR
Application Dilute: Lyophilized from a 0.22 µm filtered solution of 50 mM Tris, 150 mM NaCl, 10% Glycerol, 1 mM TCEP, pH 7.5. Contact us for customized product form or formulation.
Application Notes: Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein