Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein, E. coli
Catalog Number:
ABB-RP03285
Product Overview
Article Name:
Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein, E. coli
Biozol Catalog Number:
ABB-RP03285
Supplier Catalog Number:
RP03285
Alternative Catalog Number:
ABB-RP03285-10UG,ABB-RP03285-50UG
Manufacturer:
ABclonal
Host:
E. coli
Category:
Proteine/Peptide
Species Reactivity:
Human
Immunogen:
Met1-Val390
Alternative Names:
NCF1, NOXO2, SH3PXD1A, NCF-47K, NCF-1, p47-phox, Nox organizer 2, Neutrophil cytosol factor 1, Neutrophil NADPH oxidase factor 1, 47 kDa neutrophil oxidase factor, 47 kDa autosomal chronic granulomatous disease protein
Product Description
NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This protein is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Mutations in the NCF1 gene have been associated with chronic granulomatous disease.
Product Properties
Concentration:
< 1 EU/µg of the protein by LAL method.
Molecular Weight:
45.6 kDa
NCBI:
653361
UniProt:
P14598
Purity:
95 % as determined by SDS-PAGE.
Form:
Lyophilized from a 0.22 µm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Contact us for customized product form or formulation.
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEV
Target:
NCF1
Application Notes
Application Dilute:
Lyophilized from a 0.22 µm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Please contact us for reconstitution instructions. ResearchArea: Other Recombinant Protein