Recombinant Human Insulin Protein, Yeast

Product Overview

• Article Name: Recombinant Human Insulin Protein, Yeast
• Biozol Catalog Number: ABB-RP03297
• Supplier Catalog Number: RP03297
• Alternative Catalog Number: ABB-RP03297-20MG,ABB-RP03297-50MG
• Manufacturer: ABclonal
• Host: Yeast
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: INS, Insulin, Cleaved into: Insulin B chain, Insulin A chain

Product Description

INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.

Product Properties

• Concentration: 20 EU/mg of the protein by LAL method.
• Molecular Weight: 5.8 kDa
• NCBI: 3630
• UniProt: P01308
• Purity: 95 % as determined by SDS-PAGE.
• Form: Lyophilized from a 0.22 µm filtered solution .
• Sequence: (alphalpha chain:G-I-V-E-Q-C-C-T-S-I-C-S-L-Y-Q-L-E-N-Y-C-N beta chain: F-V-N-Q-H-L-C-G-S-H-L-V-E-A-L-Y-L-V-C-G-E-R-G-F-F-Y-T-P-K-T)
• Target: Insulin

Application Notes

• Application Dilute: Lyophilized from a 0.22 µm filtered solution .
• Application Notes: Cross-Reactivity: It is recommended to redissolve in sterile 0.01 M HCl at a concentration of not less than 1mg/mL. ResearchArea: Other Recombinant Protein