Recombinant Human LGR5 / GPR49 protein
Catalog Number:
ABB-RP03501
Product Overview
Article Name:
Recombinant Human LGR5 / GPR49 protein
Biozol Catalog Number:
ABB-RP03501
Supplier Catalog Number:
RP03501
Alternative Catalog Number:
ABB-RP03501-100UG
Manufacturer:
ABclonal
Host:
Human
Category:
Proteine/Peptide
Immunogen:
Gly 22 - Arg 561
Alternative Names:
LGR5, GPR49, GPR67,Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38
Product Description
LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/beta-catenin signaling by enhancing Wnt-induced LRP6 phosphor
Product Properties
Concentration:
< 1.0 EU/µg of the protein by LAL method.
Molecular Weight:
86.8 kDa
NCBI:
8549
UniProt:
O75473
Purity:
> 90 % as determined by SDS-PAGE
Form:
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
Sequence:
GSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK
Target:
LGR5
Application Notes
Application Dilute:
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.
