Recombinant Mouse FGF-18 Protein is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that FGF18 is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. FGF18 appears to regulate cell proliferation and differentiation positively in osteogenesis and negatively in chondrogenesis.
Lyophilized from sterile 20 mM Mes, 500 mM NaCl, 1 mM EDTA, pH 6.6.Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Target:
Fgf18
Application Dilute:
Lyophilized from sterile 20 mM Mes, 500 mM NaCl, 1 mM EDTA, pH 6.6.Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Application Notes:
ResearchArea: Cytokines & Cytokine receptors
Recombinant Mouse FGF-18 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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