Human SIRPalpha Monoclonal Antibody

Product Overview

• Article Name: Human SIRPalpha Monoclonal Antibody
• Biozol Catalog Number: ABB-YR0021
• Supplier Catalog Number: YR0021
• Alternative Catalog Number: ABB-YR0021-20MG,ABB-YR0021-5MG,ABB-YR0021-1MG
• Manufacturer: ABclonal
• Category: Antikörper
• Application: ELISA, NeA
• Alternative Names: SIRPA, BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1

Product Description

Anzurstobart (CC-95251, BMS-986351) is a high-affinity, fully human monoclonal anti-SIRPalpha antibody that blocks the binding of CD47 to SIRPalpha. Anzurstobart enhances macrophage phagocytic activity against DLBCL cell lines in co-culture models when combined with the antibody Rituximab (HY-P9913). Anzurstobart has the potential for solid and hematologic malignancies research.

Product Properties

• NCBI: 140885
• UniProt: P78324
• Purity: >95% Determined by SDS-PAGE
• Target: SIRPalpha

Application Notes

• Application Notes: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay